CD4/CD8 Ratio――Clinical Study on the Effectiveness of RE Therapy for HIV infection/AIDS

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Group RH: subject group with RE therapy and HAART (N = 20)
Group H: subject group with HAART (N = 20)
Group R: subject group with RE therapy (N = 10)
Group U: Untreated subject group (N = 10)

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Change in CD4/CD8 Ratio

Group RH

After 12 weeks of RE therapy and HAART, the mean CD4/CD8 ratio increased by 0.122 (p = 0.00155). Of the 20 subjects, CD4/CD8 ratio increased in 18 and decreased in 2.

Group H

After 12 weeks of HAART, the mean CD4/CD8 ratio decreased by 0.009 (p = 0.710). Of the 20 subjects, CD4/CD8 ratio increased in 9 and decreased in 11.

Group R

After 12 weeks of HAART, the mean CD4/CD8 ratio increased by 0.070 (p = 0.153). Of the 20 subjects, CD4/CD8 ratio increased in 6 and decreased in 4.

Group U

After 12 weeks in the untreated group, the mean CD4/CD8 ratio decreased by 0.045 (p = 0.156). Of the 10 subjects, CD4/CD8 ratio increased in 3 and decreased in 7.

Implication from the Above Outcomes

The above outcomes showed that combining HAART with RE therapy effectively increased CD4/CD8 ratio.

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